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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIP5K1B
All Species:
28.79
Human Site:
S279
Identified Species:
70.37
UniProt:
O14986
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14986
NP_003549.1
540
61036
S279
G
I
H
F
L
D
H
S
L
K
E
K
E
E
E
Chimpanzee
Pan troglodytes
XP_001137042
540
60994
S279
G
I
H
F
L
D
H
S
L
K
E
K
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001088891
535
60821
S274
G
I
H
F
L
D
H
S
L
K
E
K
E
E
E
Dog
Lupus familis
XP_533533
740
82433
T296
G
I
H
I
L
D
H
T
L
K
E
K
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P70181
539
60785
S279
G
I
H
I
L
D
H
S
L
K
D
K
E
E
E
Rat
Rattus norvegicus
Q5CZZ9
539
60715
S279
G
I
H
I
L
D
H
S
L
K
D
K
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505902
612
68141
T279
G
I
H
V
L
D
H
T
L
K
E
K
E
G
E
Chicken
Gallus gallus
Q5ZJ58
540
60700
N279
G
I
H
V
L
N
S
N
V
R
E
K
E
G
E
Frog
Xenopus laevis
NP_001085811
537
60699
T279
G
V
H
V
L
G
S
T
S
K
E
K
E
G
E
Zebra Danio
Brachydanio rerio
Q6IQE1
416
47361
H159
S
E
E
V
A
D
M
H
N
I
L
S
E
Y
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.7
70.5
N.A.
96.3
95.7
N.A.
79.5
86.6
81.4
25.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
95.7
72
N.A.
97.5
97
N.A.
83.6
93.5
89.2
41.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
80
53.3
53.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
80
66.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
80
0
0
0
0
20
0
0
0
0
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
70
0
100
60
90
% E
% Phe:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
90
0
0
0
0
10
0
0
0
0
0
0
0
30
0
% G
% His:
0
0
90
0
0
0
70
10
0
0
0
0
0
0
10
% H
% Ile:
0
80
0
30
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
80
0
90
0
0
0
% K
% Leu:
0
0
0
0
90
0
0
0
70
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
20
50
10
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% T
% Val:
0
10
0
40
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _